WebJan 6, 2024 · Search life-sciences literature (42,055,996 articles, preprints and more) Search. Advanced search WebMar 17, 2024 · In March 2024, the U.S. Food and Drug Administration (FDA) approved the first ICB drug, a PD-L1 antibody called Atezolizumab (Tecentriq) in combination with a chemotherapy agent, for the treatment of triple-negative metastatic breast cancer patients (TNBC) (NCT02425891) ( Schmid et al., 2024; Emens et al., 2024 ).
Editorial: Novel biomarkers for anticancer therapy
WebFeb 22, 2024 · These data, though early, suggest tolerability and early signs of some activity even in a patient who had 7 prior lines of therapy. We are enthusiastic, cautiously. This is … WebThis Research Topic aims to focus on novel biomarkers to be associated with anti-cancer drugs, including those related to the epigenetic regulation of cancer and drug response. … chilly outline images
Abstract LB201: A novel combination of - aacrjournals.org
WebFeb 12, 2024 · Ferroptosis is an intracellular iron-dependent form of cell death that is distinct from apoptosis, necrosis, and autophagy. Extensive studies suggest that ferroptosis plays a pivotal role in tumor suppression, thus providing new opportunities for cancer therapy. The development of resistance to cancer therapy remains a major challenge. WebDec 1, 2015 · Extracellular vesicles, particularly small exosomes with a size between 40 and 120 nm, contain complex information. Most importantly, exosomes may transfer this information to recipient cells and alter their cellular programme. If decoded, this information reveals ongoing malignant processes within the organism such as drug resistance or … WebApr 14, 2024 · With a few notable exceptions, genomically-matched, single-agent anticancer therapies rarely achieve durable clinical benefit. Therefore, the NCI and National Clinical Trials Network have developed ComboMATCH, a coordinated set of clinical trials that each test a rational, targeted drug combination therapy selected on the basis of strong … grade 10 math review