WebFeb 10, 2016 · Growth-associated protein 43 (GAP43), a protein kinase C (PKC)-activated phosphoprotein, is often implicated in axonal plasticity and regeneration. In this study, we found that GAP43 can be induced by the endotoxin lipopolysaccharide (LPS) in rat brain astrocytes both in vivo and in vitro. The LPS-induced astrocytic GAP43 expression … WebJul 24, 2024 · Moreover, quantification of growth associated protein (GAP-43) and nerve growth factor (NGF) receptor (tropomyosin receptor kinase A, TrkA) were analyzed by RT-qPCR, as previously described in 2.2. The primers used for GAP-43 and TrkA mRNA amplification can be consulted in S1 Table ( S1 Table )).
A Conditioning Sciatic Nerve Lesion Triggers a Pro ... - PubMed
WebWestern blot analysis confirmed significant changes in the expression of some of these proteins – growth associated protein-43 (GAP-43), elongation factor 1 (EF1-α1), synaptopodin, α actinin, and excitatory amino acid transporter-2 (EAAT2). Protein-level changes, such as those demonstrated in the present study, likely affect dendritic spine ... WebGrowth Associated Protein 43 (also known as GAP43) is a membrane-associated phosphoprotein encoded by the GAP43 gene in humans. It is expressed in neuronal growth cones and Schwann cell precursors during neural development, axonal regeneration and also in malignant peripheral nerve sheath tumors. It acts as a highly sensitive and useful ... saints uniforms today
Gap-43 Protein - an overview ScienceDirect Topics
WebGAP43, growth associated protein 43 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog GAP43, growth associated protein 43. Synonyms B-50, GAP-43, PP46 ... WebGAP43 (growth associated protein 43, also called B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1) is a major component of motile "growth cones" that form the tips of elongating axons as well as the synaptic plasma membranes. GAP43 is associated with nerve growth process and … WebGAP-43 is a neuron-specific phosphoprotein that has been linked with the development and functional modulation of synaptic relationships. cDNAs for the human GAP-43 gene were used to reveal high overall levels of GAP-43 mRNA in a number of integrative areas of the neocortex, but low levels in cortical areas involved in the initial processing of sensory … thingiverse base tablet