WebAug 7, 2003 · RATIONALE: Cyproheptadine and megestrol may improve appetite and help prevent weight loss in children with cancer. PURPOSE: This phase II trial is studying how well cyproheptadine and megestrol work in improving appetite and preventing weight loss in children with cachexia caused by cancer or cancer treatment. Detailed Description: … WebAug 25, 2024 · What Are Side Effects Associated with Using Cyproheptadine? Common side effects of cyproheptadine include: Abnormal facial movements ( dyskinesia) Acute labyrinthitis Blurred vision Central nervous system (CNS) depression Chills Cholestasis Constipation Delirium Diarrhea Disturbed coordination/loss of coordination Dizziness …
Cyproheptadine in Preventing Weight Loss in Children Receiving ...
WebJan 1, 2016 · Cyproheptadine, a serotonin antagonist, has recently been reported to function as a novel therapeutic agent by inhibiting PI3K/AKT signaling in several … WebCyproheptadine relieves red, irritated, itchy, watery eyes; sneezing; and runny nose caused by allergies, irritants in the air, and hay fever. It may also be used to relieve the itching of allergic skin conditions, and to treat hives, including hives caused by exposure to cold temperatures and by rubbing the skin. navigation link action definition
Cyproheptadine, an antihistaminic drug, inhibits ... - BMC Cancer
WebCyproheptadine is a histamine-1 receptor antagonist with nonspecific 5-HT1A and 5-HT2A antagonistic properties . It also has weak anticholinergic activity. Cyproheptadine is … WebOct 20, 2024 · Cyproheptadine was discovered to be able to treat not only HCC, but bladder cancer as well . There was a first animal model of cyproheptadine in the treatment of urothelial carcinoma ( 12 ). It demonstrated that cyproheptadine shrunk the size of the tumors in the experimental animal. WebAug 1, 2008 · Thus, cyproheptadine represents a lead for a novel therapeutic agent for the treatment of malignancy. Because the drug is well tolerated and already approved in multiple countries for clinical use as an antihistamine and appetite stimulant, it could be moved directly into clinical trials for cancer. navigationlink action